There are more than 224 medications currently available to treat Psoriasis. Some are available Over-the-counter (OTC), and most are available only through prescription (Rx). Some are available both ways. There are topical ointments, gels and creams. There are shampoos. There are medications taken orally, such as Psorclear. Some medications are taken through injection. Some require strict monitoring. Some require no monitoring at all. They all offer varying degrees of relief, some with virtually none and merely help relieve the itching and reduce the scale, which does not treat the problem. All have some side effects, ranging from minor irritation to severe side effects, even possible death. Some have been developed as a cure-all to treat a variety of afflictions and diseases, not just Psoriasis. Some, including all the biologics, are immuno-suppressants, like Methotrexate, which can have severe potential side effects and are also used in cancer chemotherapy.

The success rates for these drugs are from 30% to 70% and the level of clarity achieved is, at best 80%.

8-MOP (Rx)
Acitretin (Rx)
Aclovate (Rx)
Acthar (Rx)
Adalimumab (Rx)
Ala-Cort (Rx/OTC)
Ala-Scalp (Rx/OTC)
Ala-Scalp HP (Rx/OTC)
alcometasone (Rx)
amcinonide (Rx)
Amievita (Rx)
amonium lactate/halobetasol (Rx)
amonium lactate/urea (Rx/OTC)
Analpram E (Rx)
Analpram HC (Rx)
Anthraforte (Rx)
Anthralin (Rx)
Anthrascalp (Rx)
Apexicon (Rx)
Apexicon E (Rx)
Aquanil HC (Rx/OTC)
Aristocort A (Rx)
Aristocort R (Rx)
Aristospan (Rx)
Balnetar (Rx/OTC)
Beta HC (Rx/OTC)
Betamethasone/calcipotriene (Rx)
Betatar Gel (Rx/OTC)
Bioelements Immediate Comfort (Rx/OTC)
calcipotriene (Rx)
Calcitrene (Rx)
Calcitriol (Rx)
Caldecort (Rx/OTC)
Capex (Rx/OTC)
Carb-O-Lac HP (Rx/OTC)
Carb-O-Lac5 (Rx/OTC)
Cetacort (Rx/OTC)
Cinolar (Rx)
Clinacort (Rx)
Clobetasol (Rx)
Clobevate (Rx)
Clobex (Rx)
Clocortolone (Rx)
Clodan (Rx)
Cloderm (Rx)
Coal-tar (Rx/OTC)
Coal-tar/salicylic acid (OTC)
Coal-tar/salicylic acid/sulfur (OTC)
Cordran (Rx)
Cordran SP (Rx)
Cordran Tape (Rx)
Cormax (Rx)
Cormax Scalp (Rx)
Cortaid (Rx/OTC)
Corticaine (Rx/OTC)

Corticotripin (Rx)
Cortizone-10 (Rx/OTC)
Cortizone-5 (Rx/OTC)
Cosentyx (Rx)
Cotacort (Rx/OTC)
Cutar (Rx/OTC)
Cyclocort (Rx)
Cyclosporine (Rx)
Cyltezo (Rx)
Denorex Theraputic Protection (Rx/OTC)
Dermarest Plus Anti-Itch (Rx/OTC)
Derma-Smoothe/FS (Rx/OTC)
Derma-Smoothe/FS (Body Oil) (Rx/OTC)
Derma-Smoothe/FS (Scalp) (Rx/OTC)
Dermasorb HC (Rx/OTC)
Dermatop (Rx)
Dermovate (Rx)
Dermtex HC (Rx/OTC)
Desonate (Rx)
Desonide (Rx)
DesOwen (Rx)
Desoximetasone (Rx)
Dexamethasone (Rx)
DHS Tar Shampoo (Rx/OTC)
Diflorasone (Rx)
Diprolene (Rx)
Doak Tar (Rx/OTC
Dovonex (Rx)
Drithocreme (Rx)
Dritho-Scalp (Rx)
Elocon (Rx)
Elta Tar (Rx/OTC)
Embeline (Rx)
Embeline E (Rx)
Enbrel (Rx)
Enstilar (Rx)
ENTYVIO (Rx)
Epifoam (Rx/OTC)
Estar (Rx)
EtanerceptOFF LABEL (Rx)
Florone (Rx/OTC)
Fluocinolone (Rx)
Fluocinonide (Rx)
Fluocinonide-E (Rx)
Flurandrenolide (Rx)
Flurosyn (Rx/OTC)
Fototar (Rx/OTC)
Gengraf (Rx)
Gly-Cort (Rx/OTC)
H.P. Acthar Gel (Rx)
Halcinonide (Rx)
halobetasol (Rx)
Halog (Rx)
Halog-E (Rx)
Halonate (Rx)

HC Pram (Rx)
Humira (Rx)
Hydrocortisone (Rx/OTC)
Hydrocortisone/pramoxine (Rx)
Hydroxyurea (Off Label) (Rx)
Hytone (Rx/OTC)
Impoyz (Rx)
Inflectra (Rx)
Infliximab (Rx)
Instacort (Rx/OTC)
Jonil T (Rx/OTC)
Jonil T Plus (Rx/OTC)
Itch-X Lotion (Rx/OTC)
Ixifi (Rx)
Kenalog (Rx)
Kenalog-10 (Rx)
Kenalog-40 (Rx)
Kerasal Ultra 20 (Rx/OTC)
Keratol HC (Rx/OTC)
Lacticare-HC (Rx/OTC)
Locoid (Rx/OTC)
Locoid Lipocream (Rx/OTC)
LoKara (Rx)
Maxiflor (Rx)
Medotar (Rx/OTC)
Methotrexate (Rx)
Methoxsalen (Rx)
Methylprednisolone (Rx)
MG217 Medicated Tar (Rx/OTC)
Mometasone (Rx)
Neoral (Rx)
Neutrogena T/Derm (Rx/OTC)
Neutrogena T/Gel (Rx/OTC)
Nolix (Rx)
Novacort (Rx)
Nucort (Rx/OTC)
Nutracort (Rx/OTC)
Olux (Rx)
Olux/Olux-E Kit (Rx)
Olux-E (Rx)
Otezla (Rx)
Otrexup (Rx)
Oxipor VHC (Rx/OTC)
Oxsoralen-Ultra (Rx)
Pandel (Rx/OTC)
Pediaderm HC (Rx/OTC)
Pediaderm TA (Rx)
Pramasone (Rx)
Pramasone E (Rx)
Prednicarbate (Rx)
Prednisone (Rx)
Proctofoam HC (Rx)
Psorcon (Rx)
Psorcon E (Rx)
Psoriasin (Rx/OTC)

Psoriatec (Rx)
Psorigel (Rx/OTC)
R A Acne (Rx/OTC)
Rasuvo (Rx)
Recort Plus (Rx/OTC)
Remicade (Rx)
Renflexis (Rx)
Resinol (Rx/OTC)
Resorcinol (Rx/OTC)
Sarnol-HC (Rx/OTC)
Scalacort (Rx/OTC)
Scalp-Cort (Rx/OTC)
Scytera (Rx/OTC)
Siliq (Rx)
Soriatane (Rx)
Sorilux (Rx)
Stelara (Rx)
Synalar (Rx/OTC)
Synalar Ointment (Rx/OTC)
Talconex (Rx)
Talconex Scalp (Rx)
Tacrolimus (Rx)
Taltz (Rx)
Tarsum (Rx/OTC)
Tazarotene (Rx)
Tazorac (Rx)
Tegrin Medicated (Rx/OTC)
TREMFYA (Rx)
Temoyate (Rx)
Temoyate E (Rx)
Texacort (Rx/OTC)
Theraplex T (Rx/OTC)
Topicort (Rx)
Trexall (Rx)
Tremfya (Rx)
Triacet (Rx)
Triamcinolone (Rx)
Triamcinolone (Rx)
Trianex (Rx)
Triderm (Rx)
Tridesilon (Rx)
U-Cort (Rx/OTC)
Ultralytic (Rx/OTC)
Ultralytic 2 (Rx/OTC)
Ultravate (Rx)
Ultravate PAC (Rx)
Ultravate Pack Ointment (Rx)
Ustekinumab (Rx)
Vanos (Rx)
Vectical (Rx)
Verdeso (Rx)
Westcort (Rx/OTC)
Xelianz (Rx)
Zithranol (Rx)
Zithranol-RR (Rx)